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Assessment of the specificity of a new folate-targeted photosensitizer for peritoneal metastasis of epithelial ovarian cancer to enable intraperitoneal photodynamic therapy. A preclinical study.

Identifieur interne : 000111 ( Main/Exploration ); précédent : 000110; suivant : 000112

Assessment of the specificity of a new folate-targeted photosensitizer for peritoneal metastasis of epithelial ovarian cancer to enable intraperitoneal photodynamic therapy. A preclinical study.

Auteurs : Henri Azais [France] ; Caroline Schmitt [France] ; Meryem Tardivel [France] ; Olivier Kerdraon [France] ; Aurélie Stallivieri [France] ; Céline Frochot [France] ; Nacim Betrouni [France] ; Pierre Collinet [France] ; Serge Mordon [France]

Source :

RBID : Hal:hal-01183340

Abstract

The prognosis of advanced epithelial ovarian cancer remains poor. The current treatment is the association of complete macroscopic cytoreductive surgery and platinum-based chemotherapy. It is accepted that the absence of residual disease after surgery is a key to improve prognosis. 60 % of patients treated by complete cytoreductive surgery and chemotherapy will develop peritoneal recurrence.

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Le document en format XML

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<name sortKey="Frochot, Celine" sort="Frochot, Celine" uniqKey="Frochot C" first="Céline" last="Frochot">Céline Frochot</name>
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<name sortKey="Tardivel, Meryem" sort="Tardivel, Meryem" uniqKey="Tardivel M" first="Meryem" last="Tardivel">Meryem Tardivel</name>
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